MDA-5, Human Recombinant, 100 mg melanoma differentiation-associated gene-5
Item No.
61171182
MDA-5, Human Recombinant Protein Ordering Info: Part Number Size (mg) 61171181 10 61171182 100 61171183 1000 Product Number: P007H.1 Product Type: Active recombinant protein Function: Plays a major role in the activation of antiviral responses cascade by acting as a cytoplasmic sensor of viral
Description
MDA-5, Human Recombinant Protein
Ordering Info:
Product Number: P007H.1
Product Type: Active recombinant protein
Function: Plays a major role in the activation of antiviral responses cascade by acting as a cytoplasmic sensor
of viral nucleic acids
Synonyms: RLR-2, AGS7, IDDM19, SGMRT1, Hlcd, RH116, IFIH1
UniProt: Q9BYX4
NCBI: NP_071451.2, NM_022168.4
Organism: Human
Host: Escherichia coli
Tagging: untagged
Region: 306-1014, (645-662)
Sequence: LQLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLLVEQLFRKEFQPFLKK
WYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYL
MQKLKNNRLKKENKPVIPLPQILGLTASPGVGGATKQAKAEEHILKLCANLDAFTIKTVKENLDQLKNQIQEPCKKF
AIADATREDPFKEKLLEIMTRIQTYCQMSPMSDFGTQPYEQWAIQMEKKAAKEGNRKERVCAEHLRKYNEALQIN
DTIRMIDAYTHLETFYNEEKDKKFAVIEDDLKKPLKLDETDRFLMTLFFENNKMLKRLAENPEYENEKLTKLRNTIME
QYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRTGKINLLIA
TTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVAHSGSGVIEHETVNDFREKMMYKAIHCVQN
MKPEEYAHKILELQMQSIMEKKMKTKRNIAKHYKNNPSLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELYI
VRENKALQKKCADYQINGEIICKCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLD
Calculated MW: 79.4 kDa
Preparation: five-stage chromatographic purification
Purification grade: crystallography
Purity: >90% (as determined by SDS PAGE and Size Exclusion Chromatography)
Formulation: 20 mM Tris/HCl pH 7.5, 150 mM NaCl, 20% glycerol
Activity check: active as assayed by its ability to hydrolyze ATP in the presence of RNA, using the Transcreener
ADP2 fluorescence polarization assay (BellBrook Labs)
Storage: -80C
Shipping: shipped on dry ice
Keywords: Excella
Ordering Info:
| Part Number | Size (mg) |
|---|---|
| 61171181 | 10 |
| 61171182 | 100 |
| 61171183 | 1000 |
Product Number: P007H.1
Product Type: Active recombinant protein
Function: Plays a major role in the activation of antiviral responses cascade by acting as a cytoplasmic sensor
of viral nucleic acids
Synonyms: RLR-2, AGS7, IDDM19, SGMRT1, Hlcd, RH116, IFIH1
UniProt: Q9BYX4
NCBI: NP_071451.2, NM_022168.4
Organism: Human
Host: Escherichia coli
Tagging: untagged
Region: 306-1014, (645-662)
Sequence: LQLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLLVEQLFRKEFQPFLKK
WYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYL
MQKLKNNRLKKENKPVIPLPQILGLTASPGVGGATKQAKAEEHILKLCANLDAFTIKTVKENLDQLKNQIQEPCKKF
AIADATREDPFKEKLLEIMTRIQTYCQMSPMSDFGTQPYEQWAIQMEKKAAKEGNRKERVCAEHLRKYNEALQIN
DTIRMIDAYTHLETFYNEEKDKKFAVIEDDLKKPLKLDETDRFLMTLFFENNKMLKRLAENPEYENEKLTKLRNTIME
QYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRTGKINLLIA
TTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVAHSGSGVIEHETVNDFREKMMYKAIHCVQN
MKPEEYAHKILELQMQSIMEKKMKTKRNIAKHYKNNPSLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELYI
VRENKALQKKCADYQINGEIICKCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLD
Calculated MW: 79.4 kDa
Preparation: five-stage chromatographic purification
Purification grade: crystallography
Purity: >90% (as determined by SDS PAGE and Size Exclusion Chromatography)
Formulation: 20 mM Tris/HCl pH 7.5, 150 mM NaCl, 20% glycerol
Activity check: active as assayed by its ability to hydrolyze ATP in the presence of RNA, using the Transcreener
ADP2 fluorescence polarization assay (BellBrook Labs)
Storage: -80C
Shipping: shipped on dry ice
Keywords: Excella
Item Info:
| Item Title | MDA-5, Human Recombinant, 100 mg melanoma differen |
| tiation-associated gene-5 | |
| Sales Unit of Measure | EA1 |
| Last Date/Time Modified | 3/20/2024 9:21:08 AM |
